Miller Dieker syndrome (MDS, type I lissencephaly) is a neuronal migration disorder, which is caused by deletions along the short arm of chromosome 17 (17p13.3). Recent studies would suggest that the cortical lamination in MDS is inverted, based on morphological criteria. The present neuropathological study examines the cerebral cortex from a 33-week old fetus with MDS using both neuronal and laminar-specific markers. These expression studies demonstrate a relatively preserved cortex and cort...Expand abstract
- Publication status:
- Publisher copy:
- Copyright date:
Neocortical neuronal arrangement in Miller Dieker syndrome.
Views and Downloads
If you are the owner of this record, you can report an update to it here: Report update to this record