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Specificity of reversible ADP-ribosylation and regulation of cellular processes

Abstract:

Proper and timely regulation of cellular processes is fundamental to the overall health and viability of organisms across all kingdoms of life. Thus, organisms have evolved multiple highly dynamic and complex biochemical signaling cascades in order to adapt and survive diverse challenges. One such method of conferring rapid adaptation is the addition or removal of reversible modifications of different chemical groups onto macromolecules which in turn induce the appropriate downstream outcome....

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Publication status:
Published
Peer review status:
Peer reviewed

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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Pathology Dunn School
Role:
Author
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Role:
Author
ORCID:
0000-0001-7767-0799
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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Pathology Dunn School
Role:
Author
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Grant:
Cluster of Excellence Cellular Stress Responses in Aging-Associated Diseases EXC 229
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Grant:
H2020 Marie Skłodowska-Curie Actionse 657501
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Publisher:
Taylor and Francis Publisher's website
Journal:
Critical Reviews in Biochemistry and Molecular Biology Journal website
Volume:
53
Issue:
1
Pages:
64-82
Publication date:
2017-11-03
Acceptance date:
2017-10-16
DOI:
EISSN:
1549-7798
ISSN:
1040-9238
Pubs id:
pubs:745670
URN:
uri:21cf2b8b-aac3-4546-95cf-526b940418fd
UUID:
uuid:21cf2b8b-aac3-4546-95cf-526b940418fd
Local pid:
pubs:745670
Paper number:
1

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