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Oscillations of fatty acid and glycerol release from human subcutaneous adipose tissue in vivo.

Abstract:

We sought evidence for pulsatility of lipolysis in human subcutaneous adipose tissue in vivo. Arterialized and adipose tissue venous blood samples were drawn at 2-min intervals from nine healthy subjects. This procedure was repeated during hyperinsulinemic-euglycemic clamp to remove insulin pulsatility. We found evidence for pulsatile release of both nonesterified fatty acids (NEFAs) (seven of nine subjects) and glycerol (five of six subjects) with a period of approximately 12-14 min. This pu...

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Publication status:
Published

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Publisher copy:
10.2337/diabetes.54.5.1297

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
OCDEM
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
OCDEM
Role:
Author
Journal:
Diabetes More from this journal
Volume:
54
Issue:
5
Pages:
1297-1303
Publication date:
2005-05-01
DOI:
EISSN:
1939-327X
ISSN:
0012-1797
Language:
English
Keywords:
Pubs id:
pubs:19546
UUID:
uuid:21cd4e2d-a896-4a98-990d-823bc0490a6d
Local pid:
pubs:19546
Source identifiers:
19546
Deposit date:
2012-12-19

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