The emerging bunyavirus Rift Valley fever virus (RVFV) is transmitted to humans and livestock by a large number of mosquito species. RNA interference (RNAi) has been characterized as an important innate immune defense mechanism used by mosquitoes to limit replication of positive-sense RNA flaviviruses and togaviruses; however, little is known about its role against negative-strand RNA viruses such as RVFV. We show that virus-specific small RNAs are produced in infected mosquito cells, in Dros...Expand abstract
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- American Society for Microbiology Publisher's website
- mSphere Journal website
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- Dietrich et al.
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Copyright © 2017 Dietrich et al.
This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.
RNA interference restricts Rift Valley fever virus in multiple insect systems
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