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Co-modulation of finely tuned high-gamma band activity across hemispheres in Parkinson’s disease

Abstract:

Objective: Dopaminergic treatment of patients with Parkinson’s disease can be associated with a finely tuned high-gamma (FTG) band oscillation between 60 and 90 Hz in the basal ganglia (BG) nuclei. This activity, together with suppression of excessive neural synchrony in the beta frequency band (15–30 Hz), is hypothesized to contribute to the pro-kinetic effects of dopaminergic medication. Beta activity, which high-gamma replaces, has been shown to be b...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.clinph.2013.10.001

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
Weatherall Insti. of Molecular Medicine
Role:
Author
ORCID:
0000-0002-1641-115X
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Clinical Neurosciences
Role:
Author
ORCID:
0000-0002-5201-3044
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Name:
The National Institute for Health Research Oxford Biomedical Centre
Grant:
KFO247
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Name:
Wellcome Trust
Grant:
089603
More from this funder
Name:
Medical Research Council
Grant:
G0901503
Publisher:
Elsevier
Journal:
Clinical Neurophysiology More from this journal
Volume:
125
Issue:
4
Pages:
777-785
Publication date:
2013-10-22
Acceptance date:
2013-10-01
DOI:
EISSN:
1872-8952
ISSN:
1388-2457
Pmid:
24161608
Language:
English
Keywords:
Pubs id:
pubs:436036
UUID:
uuid:21b48376-900a-47fc-bfe1-947567f85a26
Local pid:
pubs:436036
Source identifiers:
436036
Deposit date:
2018-08-24

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