Journal article
Modelling the response of vascular tumours to chemotherapy: A multiscale approach
- Abstract:
-
An existing multiscale model is extended to study the response of a vascularised tumour to treatment with chemotherapeutic drugs which target proliferating cells. The underlying hybrid cellular automaton model couples tissue-level processes (e.g. blood flow, vascular adaptation, oxygen and drug transport) with cellular and subcellular phenomena (e.g. competition for space, progress through the cell cycle, natural cell death and drug-induced cell kill and the expression of angiogenic factors)....
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- Publication status:
- Published
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- Publisher copy:
- 10.1142/S0218202506001522
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Bibliographic Details
- Journal:
- MATHEMATICAL MODELS and METHODS IN APPLIED SCIENCES
- Volume:
- 16
- Issue:
- 7
- Pages:
- 1219-1241
- Publication date:
- 2006-07-01
- DOI:
- EISSN:
-
1793-6314
- ISSN:
-
0218-2025
- Source identifiers:
-
25416
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:25416
- UUID:
-
uuid:219d8abc-1bf5-4e0e-8dff-e08af3d00202
- Local pid:
- pubs:25416
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2006
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