Journal article icon

Journal article

Modelling the response of vascular tumours to chemotherapy: A multiscale approach

Abstract:

An existing multiscale model is extended to study the response of a vascularised tumour to treatment with chemotherapeutic drugs which target proliferating cells. The underlying hybrid cellular automaton model couples tissue-level processes (e.g. blood flow, vascular adaptation, oxygen and drug transport) with cellular and subcellular phenomena (e.g. competition for space, progress through the cell cycle, natural cell death and drug-induced cell kill and the expression of angiogenic factors)....

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1142/S0218202506001522

Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MPLS, Mathematical Inst
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MPLS, Mathematical Inst
Role:
Author
Journal:
MATHEMATICAL MODELS and METHODS IN APPLIED SCIENCES
Volume:
16
Issue:
7
Pages:
1219-1241
Publication date:
2006-07-05
DOI:
EISSN:
1793-6314
ISSN:
0218-2025
URN:
uuid:219d8abc-1bf5-4e0e-8dff-e08af3d00202
Source identifiers:
25416
Local pid:
pubs:25416

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP