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Dysregulation of the hypothalamic pituitary adrenal (HPA) axis and physical performance at older ages: An individual participant meta-analysis

Abstract:

The association between functioning of the hypothalamic pituitary adrenal (HPA) axis and physical performance at older ages remains poorly understood. We carried out meta-analyses to test the hypothesis that dysregulation of the HPA axis, as indexed by patterns of diurnal cortisol release, is associated with worse physical performance. Data from six adult cohorts (ages 50-92 years) were included in a two stage meta-analysis of individual participant data. We analysed each study separately usi...

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Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
Journal:
Psychoneuroendocrinology More from this journal
Volume:
38
Issue:
1
Pages:
40-49
Publication date:
2013-01-01
DOI:
EISSN:
1873-3360
ISSN:
0306-4530
Language:
English
Keywords:
Pubs id:
pubs:368197
UUID:
uuid:218d8eac-a1d0-4a18-a6bf-380360bfa888
Local pid:
pubs:368197
Source identifiers:
368197
Deposit date:
2013-11-16

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