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Journal article

Eukaryotic domain evolution inferred from genome comparisons.

Abstract:

Comparative analyses of eukaryotic genomes are providing insights into the mode and tempo of domain family evolution. Gene duplication, the source of family expansion, far exceeds the rate of emergence of domains from non-coding sequence, and the rate of recruitment of domains into novel architectures. Domain families that appear to be restricted to certain lineages are likely to be the result of gene duplication, coupled with rapid sequence diversification. If such families are evidence of p...

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Publication status:
Published

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Publisher copy:
10.1016/j.gde.2003.10.004

Authors


Copley, RR More by this author
Goodstadt, L More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
Journal:
Current opinion in genetics and development
Volume:
13
Issue:
6
Pages:
623-628
Publication date:
2003-12-05
DOI:
EISSN:
1879-0380
ISSN:
0959-437X
URN:
uuid:21881b8d-c985-46a9-bc72-bd4a5542523a
Source identifiers:
54031
Local pid:
pubs:54031

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