Thesis icon

Thesis

Insights into the molecular mechanisms of ABC transporters and membrane insertases

Abstract:

Membrane proteins have a pivotal role in cellular homeostasis given their strategic position and involvement in pathways such as small molecules transport and interaction with ligands leading to downstream responses. In this thesis, I describe the application of mass spectrometry approaches to elucidate the structure, dynamics and regulation of membrane protein complexes, including ABC transporters and membrane insertases. The employment of native mass spectrometry (nMS) to membrane protei...

Expand abstract

Actions


Access Document


Files:

Authors


More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Physical & Theoretical Chem
Oxford college:
Kellogg College
Role:
Author
ORCID:
0000-0003-3550-1860

Contributors

Role:
Supervisor
More from this funder
Name:
Medical Research Council
Grant:
EP/L016044/1
More from this funder
Name:
Engineering and Physical Sciences Research Council
Grant:
EP/L016044/1
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP