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Nanomedicine: Engineering of a tri-imageable nanoparticle for diagnostics

Abstract:

We have created a potential targeted drug delivery platform with three imaging reporters by coupling the magnetic properties of USPIOs with near infrared fluorescence of Cy5.5 and γ-emissions of 111In that is chelated to a conjugated antibody. The nanoparticle will allow for not only triple verification of localization, but also quantification. During each phase of development, the nanoparticles have been characterized for surface charge and structure by transmission electron microscopy and d...

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Publication status:
Published

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Journal:
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY More from this journal
Volume:
238
Pages:
1-4
Publication date:
2009-08-16
ISSN:
0065-7727
Language:
English
Keywords:
Pubs id:
pubs:292569
UUID:
uuid:2170de14-e3f5-4acc-8f46-682f9f1934fc
Local pid:
pubs:292569
Source identifiers:
292569
Deposit date:
2012-12-19

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