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Field trials of an asexual blood stage malaria vaccine: studies of the synthetic peptide polymer SPf66 in Thailand and the analytic plan for a phase IIb efficacy study.

Abstract:

Several years ago the Walter Reed Army Institute of Research (WRAIR) initiated an independent analysis of the candidate malaria blood stage vaccine SPf66. WRAIR contracted for the synthesis and formulation of SPf66 in United States Food and Drug Administration (FDA) inspected laboratories within the U.S., and in 1992, filed an Investigational New Drug (IND) application with the FDA. Preclinical studies indicated that the vaccine could be synthesized to meet its release specifications, and whe...

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Publication status:
Published

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Publisher copy:
10.1017/s0031182000001463

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Journal:
Parasitology More from this journal
Volume:
110 Suppl
Issue:
SUPPL.
Pages:
S25-S36
Publication date:
1995-01-01
DOI:
EISSN:
1469-8161
ISSN:
0031-1820
Language:
English
Keywords:
Pubs id:
pubs:21746
UUID:
uuid:216961d2-2941-44bc-a313-a903fcf5d550
Local pid:
pubs:21746
Source identifiers:
21746
Deposit date:
2012-12-19

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