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Journal article

Persistent stromal fibroblast activation is present in chronic tendinopathy

Abstract:

Background

Growing evidence supports a key role for inflammation in the onset and progression of tendinopathy. However, the effects of the inflammatory infiltrate on tendon cells is poorly understood.

Methods

We investigated stromal fibroblast activation signatures in tissues and cells from patients with tendinopathy. Diseased tendons were collected from well phenotyped patient cohorts with supraspinatus tendinopathy before and after sub-acromial decompression tre...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1186/s13075-016-1218-4

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Kennedy Institute for Rheumatology
Role:
Author
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More from this funder
Funding agency for:
Dakin, S
Grant:
20506
National Institute for Health Research More from this funder
Publisher:
BioMed Central Publisher's website
Journal:
Arthritis Research and Therapy Journal website
Volume:
19
Pages:
16
Publication date:
2017-01-01
Acceptance date:
2016-12-29
DOI:
ISSN:
1478-6362
Keywords:
Pubs id:
pubs:668097
UUID:
uuid:2148d909-9a37-4855-9a17-723f8902d15a
Local pid:
pubs:668097
Deposit date:
2017-01-05

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