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Journal article

A novel desmocollin-2 mutation reveals insights into the molecular link between desmosomes and gap junctions.

Abstract:

BACKGROUND: Cellular adhesion mediated by cardiac desmosomes is a prerequisite for proper electric propagation mediated by gap junctions in the myocardium. However, the molecular principles underlying this interdependence are not fully understood. OBJECTIVE: The purpose of this study was to determine potential causes of right ventricular conduction abnormalities in a patient with borderline diagnosis of arrhythmogenic right ventricular cardiomyopathy. METHODS: To assess molecular changes, the...

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Publication status:
Published

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Publisher copy:
10.1016/j.hrthm.2011.01.010

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
RDM Cardiovascular Medicine
Role:
Author
Journal:
Heart rhythm : the official journal of the Heart Rhythm Society More from this journal
Volume:
8
Issue:
5
Pages:
711-718
Publication date:
2011-05-01
DOI:
EISSN:
1556-3871
ISSN:
1547-5271
Language:
English
Keywords:
Pubs id:
pubs:257050
UUID:
uuid:2142eca4-f938-40b6-9fa4-827f1fe68212
Local pid:
pubs:257050
Source identifiers:
257050
Deposit date:
2013-11-17

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