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White matter damage and cognitive impairment after traumatic brain injury

Abstract:

White matter disruption is an important determinant of cognitive impairment after brain injury, but conventional neuroimaging underestimates its extent. In contrast, diffusion tensor imaging provides a validated and sensitive way of identifying the impact of axonal injury. The relationship between cognitive impairment after traumatic brain injury and white matter damage is likely to be complex. We applied a flexible technique - tract-based spatial statistics - to explore whether damage to spe...

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Publisher copy:
10.1093/brain/awq347

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Journal:
Brain
Volume:
134
Issue:
2
Pages:
449-463
Publication date:
2011-02-05
DOI:
EISSN:
1460-2156
ISSN:
0006-8950
URN:
uuid:212592ff-75d7-47c6-be3e-cf7cf089b41e
Source identifiers:
377879
Local pid:
pubs:377879

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