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Analysis of centriole elimination during C. elegans oogenesis.

Abstract:

Centrosomes are the principal microtubule organizing centers (MTOCs) of animal cells and comprise a pair of centrioles surrounded by pericentriolar material (PCM). Centriole number must be carefully regulated, notably to ensure bipolar spindle formation and thus faithful chromosome segregation. In the germ line of most metazoan species, centrioles are maintained during spermatogenesis, but eliminated during oogenesis. Such differential behavior ensures that the appropriate number of centriole...

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Publisher copy:
10.1242/dev.075440

Authors


Journal:
Development (Cambridge, England) More from this journal
Volume:
139
Issue:
9
Pages:
1670-1679
Publication date:
2012-05-01
DOI:
EISSN:
1477-9129
ISSN:
0950-1991
Language:
English
Keywords:
Pubs id:
pubs:323388
UUID:
uuid:2120478a-5655-4fdc-84ab-3b2dd04eab42
Local pid:
pubs:323388
Source identifiers:
323388
Deposit date:
2013-11-17

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