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An objective short sleep insomnia disorder subtype is associated with reduced brain metabolite concentrations in vivo: a preliminary magnetic resonance spectroscopy assessment

Abstract:

Objectives: To evaluate brain metabolites in objective insomnia subtypes defined from polysomnography (PSG): insomnia with short sleep duration (I-SSD) and insomnia with normal sleep duration (I-NSD); relative to good sleeping controls.

Methods: PSG empirically grouped insomnia patients into I-SSD (n=12: mean (SD) total sleep time (TST) = 294.7min (30.5)) or I-NSD (n=19: TST = 394.4min (34.9)). 1H magnetic resonance spectroscopy acquired in the left occipital cortex (LOCC), left pr...

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Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.1093/sleep/zsx148

Authors


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Funding agency for:
Miller, C
Grant:
1060992
More from this funder
Funding agency for:
Miller, C
Grant:
1060992
More from this funder
Funding agency for:
Miller, C
Grant:
1060992
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Publisher:
Oxford University Press Publisher's website
Journal:
SLEEP Journal website
Volume:
40
Issue:
11
Pages:
1-11
Publication date:
2017-08-25
Acceptance date:
2017-08-16
DOI:
EISSN:
1550-9109
ISSN:
0161-8105
Source identifiers:
723968
Pubs id:
pubs:723968
UUID:
uuid:20dce2b2-327c-4bf2-b1a1-042171afe336
Local pid:
pubs:723968
Deposit date:
2017-08-24

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