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Journal article

Sequence of Crm1/exportin 1 mutant alleles reveals critical sites associated with multidrug resistance.

Abstract:

We have previously shown that genes involved in a novel pathway of multidrug resistance (MDR) in the fission yeast Schizosaccharomyces pombe are functionally conserved in human cells (V. Spataro et al. (1997) J Biol Chem 272: 30470-30475). The human homologue of one of these genes, hCRM1, has recently been identified and found to function in nucleocytoplasmic export, a process which controls the subcellular localization and hence activity of a number of key cell cycle regulators and transcrip...

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Publication status:
Published

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Publisher copy:
10.1007/s002940000170

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Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Role:
Author
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Journal:
Current genetics
Volume:
39
Issue:
1
Pages:
2-9
Publication date:
2001-02-05
DOI:
EISSN:
1432-0983
ISSN:
0172-8083
URN:
uuid:20a39d1c-93a6-438a-936f-4a5c9f507712
Source identifiers:
24994
Local pid:
pubs:24994

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