- Abstract:
-
Purpose The brain is a common site of metastasis for patients with high-risk melanoma. Although surgery or stereotactic radiosurgery are highly effective local treatments for a small number of metastases, there is a high risk of developing additional brain metastases. The role of adjuvant whole-brain radiotherapy (WBRT) in reducing new metastases is controversial, with a lack of high-level evidence specifically for melanoma.
Methods In this randomiz...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Publisher copy:
- 10.1200/JCO.19.01414
-
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- Publisher:
- American Society of Clinical Oncology Publisher's website
- Journal:
- Journal of Clinical Oncology Journal website
- Volume:
- 37
- Issue:
- 33
- Pages:
- 3132-3141
- Publication date:
- 2019-09-25
- Acceptance date:
- 2019-08-07
- DOI:
- ISSN:
-
1527-7755
- Pubs id:
-
pubs:1039841
- UUID:
-
uuid:2099f136-5939-45ab-8bbf-4ca44579dc67
- Source identifiers:
-
1039841
- Local pid:
- pubs:1039841
- Language:
- English
- Keywords:
- Copyright holder:
- American Society of Clinical Oncology
- Copyright date:
- 2019
- Rights statement:
- Copyright © 2019 by American Society of Clinical Oncology.
- Notes:
- This is the accepted manuscript version of the article. The final version is available online from American Society of Clinical Oncology at https://doi.org/10.1200/JCO.19.01414
Journal article
Adjuvant whole-brain radiation therapy compared with observation after local treatment of melanoma brain metastases: a multicenter, randomized phase III trial
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