Journal article
Oxygenase-catalyzed ribosome hydroxylation occurs in prokaryotes and humans.
- Abstract:
-
The finding that oxygenase-catalyzed protein hydroxylation regulates animal transcription raises questions as to whether the translation machinery and prokaryotic proteins are analogously modified. Escherichia coli ycfD is a growth-regulating 2-oxoglutarate oxygenase catalyzing arginyl hydroxylation of the ribosomal protein Rpl16. Human ycfD homologs, Myc-induced nuclear antigen (MINA53) and NO66, are also linked to growth and catalyze histidyl hydroxylation of Rpl27a and Rpl8, respectively. ...
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- Publication status:
- Published
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Bibliographic Details
- Journal:
- Nature chemical biology
- Volume:
- 8
- Issue:
- 12
- Pages:
- 960-962
- Publication date:
- 2012-12-01
- DOI:
- EISSN:
-
1552-4469
- ISSN:
-
1552-4450
- Source identifiers:
-
368114
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:368114
- UUID:
-
uuid:20947b6a-1e4e-4bb5-951b-4d57edee4d70
- Local pid:
- pubs:368114
- Deposit date:
- 2013-11-16
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- Copyright date:
- 2012
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