Journal article icon

Journal article

Susceptibility to rheumatoid arthritis is not associated with a single common allele of the type 2 collagen gene (COL2A1)

Abstract:

Type 2 collagen is quantitatively the most important constituent of articular cartilage which is the target of progressive destruction in RA. Polymorphism of type 2 collagen could theoretically influence the development of RA either by rendering the cartilage matrix particularly susceptible to autoimmune attack or subsequent degradation. We have investigated the possibility that there is a common allele of type 2 collagen associated with RA by analysing a dimorphism of the corresponding struc...

Expand abstract
Publication status:
Published

Actions


Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Journal:
British journal of rheumatology
Volume:
32
Issue:
6
Pages:
456-457
Publication date:
1993-06-05
ISSN:
0263-7103
URN:
uuid:204459e2-6173-4a87-99c9-9f94703d21ba
Source identifiers:
108643
Local pid:
pubs:108643

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP