- Abstract:
-
Surface glycoproteins direct cellular targeting, attachment, and membrane fusion of arenaviruses and are the primary target for neutralizing antibodies. Despite significant conservation of the glycoprotein architecture across the arenavirus family, there is considerable variation in the molecular recognition mechanisms used during host cell entry. We review recent progress in dissecting these infection events and describe how arenaviral glycoproteins can be targeted by small-molecule antivira...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
- Publisher:
- Elsevier Publisher's website
- Journal:
- Current Opinion in Virology Journal website
- Volume:
- 18
- Pages:
- 70-75
- Publication date:
- 2016-04-05
- Acceptance date:
- 2016-04-04
- DOI:
- EISSN:
-
1879-6265
- ISSN:
-
1879-6257
- Pubs id:
-
pubs:613759
- URN:
-
uri:2044485d-e4a8-44df-991f-b27c0213db3d
- UUID:
-
uuid:2044485d-e4a8-44df-991f-b27c0213db3d
- Local pid:
- pubs:613759
- Copyright holder:
- Bowden et al
- Copyright date:
- 2016
- Notes:
- © 2016 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
Journal article
Native functionality and therapeutic targeting of arenaviral glycoproteins.
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Neutralizing Antibody Consortium
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