Journal article
Native functionality and therapeutic targeting of arenaviral glycoproteins.
- Abstract:
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Surface glycoproteins direct cellular targeting, attachment, and membrane fusion of arenaviruses and are the primary target for neutralizing antibodies. Despite significant conservation of the glycoprotein architecture across the arenavirus family, there is considerable variation in the molecular recognition mechanisms used during host cell entry. We review recent progress in dissecting these infection events and describe how arenaviral glycoproteins can be targeted by small-molecule antivira...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Access Document
- Files:
-
-
(Version of record, pdf, 707.3KB)
-
- Publisher copy:
- 10.1016/j.coviro.2016.04.001
Authors
Funding
Neutralizing Antibody Consortium
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Bill and Melinda Gates Collaboration for AIDS Vaccine Discovery
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Bibliographic Details
- Publisher:
- Elsevier Publisher's website
- Journal:
- Current Opinion in Virology Journal website
- Volume:
- 18
- Pages:
- 70-75
- Publication date:
- 2016-04-01
- Acceptance date:
- 2016-04-04
- DOI:
- EISSN:
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1879-6265
- ISSN:
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1879-6257
- Pmid:
-
27104809
- Source identifiers:
-
613759
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:613759
- UUID:
-
uuid:2044485d-e4a8-44df-991f-b27c0213db3d
- Local pid:
- pubs:613759
- Deposit date:
- 2017-12-21
Terms of use
- Copyright holder:
- Bowden et al
- Copyright date:
- 2016
- Notes:
- © 2016 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
- Licence:
- CC Attribution (CC BY)
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