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Effects of acute ketamine infusion on visual working memory: event-related potentials

Abstract:

Background: Working memory (WM) deficits are a core feature of schizophrenia. Electrophysiological studies suggest that impaired early visual processing may contribute to impaired WM in the visual domain. Abnormal . N-methyl-D-aspartate (NMDA) receptor function has been implicated both in WM and in early visual processing deficits in schizophrenia. We investigated whether ketamine, a noncompetitive NMDA antagonist, would replicate in healthy volunteers the WM performance and early visual proc...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.bpsc.2016.09.008

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Department:
Oxford, MSD, Psychiatry
Role:
Author
Welsh Institute of Cognitive Neuroscience More from this funder
Publisher:
Elsevier Publisher's website
Journal:
Biological Psychiatry: Cognitive Neuroscience and Neuroimaging Journal website
Publication date:
2016-01-01
DOI:
ISSN:
2451-9022
Pubs id:
pubs:669011
URN:
uri:203b60b0-8978-4c2f-83f6-3f711769ba69
UUID:
uuid:203b60b0-8978-4c2f-83f6-3f711769ba69
Local pid:
pubs:669011

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