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Common genetic variants influence human subcortical brain structures.

Abstract:

The highly complex structure of the human brain is strongly shaped by genetic influences. Subcortical brain regions form circuits with cortical areas to coordinate movement, learning, memory and motivation, and altered circuits can lead to abnormal behaviour and disease. To investigate how common genetic variants affect the structure of these brain regions, here we conduct genome-wide association studies of the volumes of seven subcortical regions and the intracranial volume derived from magn...

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Publication status:
Published

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Publisher copy:
10.1038/nature14101

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Journal:
Nature
Volume:
520
Issue:
7546
Pages:
224-229
Publication date:
2015-04-05
DOI:
EISSN:
1476-4687
ISSN:
0028-0836
URN:
uuid:202609ba-9ab3-4aa2-8abd-7ce9e9070635
Source identifiers:
504670
Local pid:
pubs:504670

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