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Journal article

Pore geometry regulates early stage human bone marrow cell tissue formation and organisation.

Abstract:

Porous architecture has a dramatic effect on tissue formation in porous biomaterials used in regenerative medicine. However, the wide variety of 3D structures used indicates there is a clear need for the optimal design of pore architecture to maximize tissue formation and ingrowth. Thus, the aim of this study was to characterize initial tissue growth solely as a function of pore geometry. We used an in vitro system with well-defined open pore slots of varying width, providing a 3D environment...

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Publication status:
Published

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Publisher copy:
10.1007/s10439-013-0748-z

Authors


Knychala, J More by this author
Bouropoulos, N More by this author
Katsamenis, OL More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MPLS, Mathematical Inst
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Journal:
Annals of biomedical engineering
Volume:
41
Issue:
5
Pages:
917-930
Publication date:
2013-05-05
DOI:
EISSN:
1573-9686
ISSN:
0090-6964
URN:
uuid:1ffd97d4-05ea-46e2-8d6d-b1d58883ed9e
Source identifiers:
384358
Local pid:
pubs:384358

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