Journal article
The PA subunit is required for efficient nuclear accumulation of the PB1 subunit of the influenza A virus RNA polymerase complex.
- Abstract:
-
The RNA genome of influenza virus is transcribed and replicated by the viral RNA polymerase complex in the cell nucleus. We have generated green fluorescent protein (GFP)-tagged polymerase subunits to study the assembly of the polymerase complex. Our results show that individually expressed polymerase basic protein 1 (PB1) and polymerase acidic protein (PA) subunits were distributed in both the cytoplasm and the nucleus, while the polymerase basic protein 2 (PB2) subunit accumulated in the nu...
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- Publication status:
- Published
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- Publisher copy:
- 10.1128/jvi.78.17.9144-9153.2004
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Authors
Bibliographic Details
- Journal:
- Journal of virology
- Volume:
- 78
- Issue:
- 17
- Pages:
- 9144-9153
- Publication date:
- 2004-09-01
- DOI:
- EISSN:
-
1098-5514
- ISSN:
-
0022-538X
- Source identifiers:
-
30856
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:30856
- UUID:
-
uuid:1ff4233c-91ee-4619-a47a-777a3533e79d
- Local pid:
- pubs:30856
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2004
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