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Journal article

Identification of a new subset of lymph node stromal cells involved in regulating plasma cell homeostasis

Abstract:

Antibody-secreting plasma cells (PCs) arise rapidly during adaptive immunity to control infections. The early PCs are retained within the reactive lymphoid organ where their localization and homeostasis rely on extrinsic factors, presumably produced by local niche cells. While myeloid cells have been proposed to form those niches, the contribution by colocalizing stromal cells has remained unclear. Here, we characterized a subset of fibroblastic reticular cells (FRCs) that forms a dense me...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted manuscript

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Publisher copy:
10.1073/pnas.1712628115

Authors


Rivas-Caicedo, A More by this author
Renevey, F More by this author
Cannelle, H More by this author
Peranzoni, E More by this author
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Swiss National Science Foundation More from this funder
French National Research Council More from this funder
Taiwan National Science Council More from this funder
French League Against Cancer More from this funder
Cancer Research for Personalized Medicine More from this funder
Publisher:
National Academy of Sciences Publisher's website
Journal:
Proceedings of the National Academy of Sciences Journal website
Volume:
115
Issue:
29
Pages:
E6826-E6835
Publication date:
2018-07-02
Acceptance date:
2018-05-25
DOI:
EISSN:
1091-6490
ISSN:
0027-8424
Pubs id:
pubs:854173
URN:
uri:1ff0ff72-d68f-412f-b7a3-677dc47ad2e2
UUID:
uuid:1ff0ff72-d68f-412f-b7a3-677dc47ad2e2
Local pid:
pubs:854173

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