Journal article
Comprehensive, quantitative mapping of T cell epitopes in gluten in celiac disease.
- Abstract:
-
Celiac disease is a genetic condition that results in a debilitating immune reaction in the gut to antigens in grain. The antigenic peptides recognized by the T cells that cause this disease are incompletely defined. Our understanding of the epitopes of pathogenic CD4(+ )T cells is based primarily on responses shown by intestinal T-cells in vitro to hydrolysates or polypeptides of gluten, the causative antigen. A protease-resistant 33-amino acid peptide from wheat alpha-gliadin is the immunod...
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- Publication status:
- Published
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- Publisher copy:
- 10.1126/scitranslmed.3001012
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Authors
Bibliographic Details
- Journal:
- Science translational medicine
- Volume:
- 2
- Issue:
- 41
- Pages:
- 41ra51
- Publication date:
- 2010-07-01
- DOI:
- EISSN:
-
1946-6242
- ISSN:
-
1946-6234
- Source identifiers:
-
94840
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:94840
- UUID:
-
uuid:1fcd70f9-d7f2-4e9c-b4b1-e3c99e82e82d
- Local pid:
- pubs:94840
- Deposit date:
- 2012-12-19
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- Copyright date:
- 2010
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