Journal article icon

Journal article

Cytotoxic T-lymphocyte epitopes for HLA-B53 and other HLA types in the malaria vaccine candidate liver-stage antigen 3.

Abstract:

The development of an effective preerythrocytic vaccine against Plasmodium falciparum malaria is likely to require inclusion of components from several preerythrocytic antigens. The association of HLA-B53 with resistance to severe malaria in West Africa provided evidence that HLA class I-restricted CD8(+) T-cell responses play a role in protective immunity in African children, supporting data from rodent models of malaria. Previously, a single epitope from liver-stage-specific antigen 1 (LSA-...

Expand abstract
Publication status:
Published

Actions


Access Document


Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Jenner Institute
Role:
Author
Expand authors...
Journal:
Infection and immunity
Volume:
68
Issue:
1
Pages:
227-232
Publication date:
2000-01-05
DOI:
EISSN:
1098-5522
ISSN:
0019-9567
URN:
uuid:1fb86545-8a72-4c90-9a1b-b8adc5fd6480
Source identifiers:
31590
Local pid:
pubs:31590

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP