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Simultaneously reconstructing viral cross-species transmission history and identifying the underlying constraints.

Abstract:

The factors that determine the origin and fate of cross-species transmission events remain unclear for the majority of human pathogens, despite being central for the development of predictive models and assessing the efficacy of prevention strategies. Here, we describe a flexible Bayesian statistical framework to reconstruct virus transmission between different host species based on viral gene sequences, while simultaneously testing and estimating the contribution of several potential predict...

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Publication status:
Published

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Publisher copy:
10.1098/rstb.2012.0196

Authors


Suchard, MA More by this author
Rambaut, A More by this author
Streicker, DG More by this author
Journal:
Philosophical transactions of the Royal Society of London. Series B, Biological sciences
Volume:
368
Issue:
1614
Pages:
20120196
Publication date:
2013-03-05
DOI:
EISSN:
1471-2970
ISSN:
0962-8436
URN:
uuid:1fa9d0ab-ec8d-47a6-93af-219f861d55ff
Source identifiers:
425922
Local pid:
pubs:425922

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