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Interaction of blood coagulation factor Va with phospholipid vesicles examined by using lipophilic photoreagents.

Abstract:

Two different lipophilic photoreagents, [3H]adamantane diazirine and 3-(trifluoromethyl)-3-(m-[125I]iodophenyl)diazirine (TID), have been utilized to examine the interactions of blood coagulation factor Va with calcium, prothrombin, factor Xa, and, in particular, phospholipid vesicles. With each of these structurally dissimilar reagents, the extent of photolabeling of factor Va was greater when the protein was bound to a membrane surface than when it was free in solution. Specifically, the co...

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Publication status:
Published

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Publisher copy:
10.1021/bi00375a015

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Journal:
Biochemistry More from this journal
Volume:
26
Issue:
1
Pages:
103-109
Publication date:
1987-01-01
DOI:
EISSN:
1520-4995
ISSN:
0006-2960
Language:
English
Keywords:
Pubs id:
pubs:52401
UUID:
uuid:1fa952fc-6b02-49d4-9f64-77ea001b3316
Local pid:
pubs:52401
Source identifiers:
52401
Deposit date:
2013-11-17

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