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Journal article

Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.

Abstract:

Genome-wide association studies (GWASs) have identified many SNPs underlying variations in plasma-lipid levels. We explore whether additional loci associated with plasma-lipid phenotypes, such as high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), total cholesterol (TC), and triglycerides (TGs), can be identified by a dense gene-centric approach. Our meta-analysis of 32 studies in 66,240 individuals of European ancestry was based on the custom ∼50,000 SN...

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Publication status:
Published

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Publisher copy:
10.1016/j.ajhg.2012.08.032

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Journal:
American journal of human genetics
Volume:
91
Issue:
5
Pages:
823-838
Publication date:
2012-11-05
DOI:
EISSN:
1537-6605
ISSN:
0002-9297
URN:
uuid:1f9eea25-1743-4fa3-bb34-d6ae7923d842
Source identifiers:
356632
Local pid:
pubs:356632

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