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Journal article

Heterogeneity of carbonyl reduction in subcellular fractions and different organs in rodents.

Abstract:

The pattern and distribution of carbonyl reduction in liver, kidney and adrenal gland subcellular fractions of NMRI mice, Wistar rats and Hartley guinea pigs were examined using the ketone compound metyrapone (2-methyl-1,2-di(3-pyridyl)1-propanone) commonly used as a diagnostic cytochrome P450 inhibitor. A direct HPLC method for alcohol metabolite determination instead of the indirect spectrophotometric recording of pyridine nucleotide oxidation at 340 nm was applied. All the tissues examined...

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Journal:
Biochemical pharmacology
Volume:
42 Suppl
Pages:
S189-S195
Publication date:
1991-12-05
DOI:
EISSN:
1873-2968
ISSN:
0006-2952
URN:
uuid:1f95be46-0a4f-4b43-b126-c47939edb8b0
Source identifiers:
108534
Local pid:
pubs:108534

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