BACKGROUND: Combining two different analgesics in fixed doses in a single tablet can provide better pain relief than either drug alone in acute pain. This appears to be broadly true across a range of different drug combinations, in postoperative pain and migraine headache. Fixed-dose combinations of ibuprofen and oxycodone are available, and the drugs may be separately used in combination in some acute pain situations. OBJECTIVES: To assess the analgesic efficacy and adverse effects of a sin...Expand abstract
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Single dose oral ibuprofen plus oxycodone for acute postoperative pain in adults.
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