Journal article
What are the markers of aggressiveness in prolactinomas? Changes in cell biology, extracellular matrix components, angiogenesis and genetics.
- Abstract:
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Prolactinoma is the most common pituitary tumour in adults. Macroprolactinomas, particularly in men, may occasionally exhibit a very aggressive clinical course as evidenced by progressive growth, invasion through bone into the sphenoid sinus, cavernous sinus, suprasellar region or the nasopharynx. Some may even progress to pituitary carcinoma with craniospinal or systemic metastases. Aggressive tumours have low cure rates despite appropriate medical and surgical treatment. The mechanisms unde...
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- Publication status:
- Published
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Bibliographic Details
- Journal:
- European journal of endocrinology / European Federation of Endocrine Societies More from this journal
- Volume:
- 156
- Issue:
- 2
- Pages:
- 143-153
- Publication date:
- 2007-02-01
- DOI:
- EISSN:
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1479-683X
- ISSN:
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0804-4643
Item Description
- Language:
-
English
- Keywords:
- Pubs id:
-
pubs:19824
- UUID:
-
uuid:1f8989d6-a0ac-4818-a582-0110eecf55c5
- Local pid:
-
pubs:19824
- Source identifiers:
-
19824
- Deposit date:
-
2012-12-19
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- Copyright date:
- 2007
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