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Journal article

Heterogeneous early immune responses to the S. aureus EapH2 antigen induced by gastrointestinal tract colonisation impact the response to subsequent vaccination

Abstract:

Introduction

S. aureus is a pathogen to which individuals are exposed shortly after birth, with immune responses to S. aureus increasing during childhood. There is marked heterogeneity between the anti- S. aureus immune responses of different humans, the basis of which is not fully understood.

Methods

To investigate development of anti-S. aureus immune responses, we studied S. aureus colonised mice under controlled conditions. Mice were either acquired colonised f...

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Publication status:
Published
Peer review status:
Peer reviewed

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
CCMP
Oxford college:
Hertford College
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM
Sub department:
NDM Experimental Medicine
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author
More from this funder
Funding agency for:
Rollier, C
Grant:
Investigator
National Institute for Health Research More from this funder
Publisher:
Elsevier Publisher's website
Journal:
Vaccine Journal website
Volume:
37
Issue:
3
Pages:
494-501
Publication date:
2018-11-28
Acceptance date:
2018-11-20
DOI:
EISSN:
1873-2518
ISSN:
0264-410X
Source identifiers:
948389
Language:
English
Keywords:
Pubs id:
pubs:948389
UUID:
uuid:1f66cdd1-f418-4a34-a761-1dde37dcc682
Local pid:
pubs:948389
Deposit date:
2018-11-29

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