Journal article icon

Journal article

Heterogeneous early immune responses to the S. aureus EapH2 antigen induced by gastrointestinal tract colonisation impact the response to subsequent vaccination

Abstract:

Introduction

S. aureus is a pathogen to which individuals are exposed shortly after birth, with immune responses to S. aureus increasing during childhood. There is marked heterogeneity between the anti- S. aureus immune responses of different humans, the basis of which is not fully understood.

Methods

To investigate development of anti-S. aureus immune responses, we studied S. aureus colonised mice under controlled conditions. Mice were either acquired colonised f...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Authors


More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM
Subgroup:
Jenner Institute
Oxford college:
Hertford College
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM
Subgroup:
NDM Experimental Medicine
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM
Subgroup:
Tropical Medicine
Role:
Author
Expand authors...
More from this funder
Funding agency for:
Rollier, C
National Institute for Health Research More from this funder
Publisher:
Elsevier Publisher's website
Journal:
Vaccine Journal website
Volume:
37
Issue:
3
Pages:
494-501
Publication date:
2018-11-28
Acceptance date:
2018-11-20
DOI:
EISSN:
1873-2518
ISSN:
0264-410X
Pubs id:
pubs:948389
URN:
uri:1f66cdd1-f418-4a34-a761-1dde37dcc682
UUID:
uuid:1f66cdd1-f418-4a34-a761-1dde37dcc682
Local pid:
pubs:948389
Language:
English
Keywords:

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP