Journal article
Enantioselective partial reduction of 2,5-disubstituted pyrroles via a chiral protonation approach.
- Abstract:
- [reaction: see text] The partial reduction of 2,5-pyrrole diester 1 followed by enantioselective protonation in situ to furnish synthetically useful building blocks is described. An enantiomeric excess of up to 74% was achieved using (-)-ephedrine and related analogues as chiral proton sources. The pyrroline product obtained could be recrystallized to give enantiomerically pure material.
- Publication status:
- Published
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Bibliographic Details
- Journal:
- Organic letters
- Volume:
- 6
- Issue:
- 18
- Pages:
- 3055-3058
- Publication date:
- 2004-09-01
- DOI:
- EISSN:
-
1523-7052
- ISSN:
-
1523-7060
- Source identifiers:
-
32824
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:32824
- UUID:
-
uuid:1f52f211-6444-4c84-959c-3db4afdb2994
- Local pid:
- pubs:32824
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2004
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