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Progress with interferon in CML--results of the MRC UK CML III study.

Abstract:

527 patients with CML were entered into the multicentre randomised MRC CML III study comparing IFN-alpha n1 to standard chemotherapy, either busulphan or hydroxyurea. Haematologic response to IFN as assessed by the level of control of the WCC predicted cytogenetic response to IFN. Cytogenetic response (< 80% Ph + ve) was seen in 22% of all patients randomised, 11% showing major or complete responses. Major cytogenetic response rate was 18% in Sokal low risk patients, 15% in intermediate ri...

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Publication status:
Published

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Volume:
17 Suppl 3
Pages:
S15-S18
Host title:
Bone marrow transplantation
Publication date:
1996-05-01
Event location:
ENGLAND
EISSN:
1476-5365
ISSN:
0268-3369
Source identifiers:
96013
Keywords:
Pubs id:
pubs:96013
UUID:
uuid:1f405193-0314-44da-bdd0-d34d70ec162c
Local pid:
pubs:96013
Deposit date:
2012-12-19

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