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Does the use of immunohistochemistry to identify micrometastases provide useful information in the staging of node-negative non-small cell lung carcinomas?

Abstract:

Immunohistochemical studies using epithelial markers have recently been published which identified micrometastases in lymph nodes that had not been found on routine pathological assessment, therefore increasing the accuracy of staging of non-small cell lung cancers. The presence of these micrometastases was associated with reduced survival. We have therefore performed a retrospective immunohistochemical study on all the lymphoid tissue from five lymph node stations (2 hilar, 3 mediastinal) fr...

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Authors


Nicholson, AG More by this author
Graham, AN More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, RDM, Clinical Lab Sciences
Goldstraw, P More by this author
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Journal:
Lung cancer (Amsterdam, Netherlands)
Volume:
18
Issue:
3
Pages:
231-240
Publication date:
1997-11-05
DOI:
EISSN:
1872-8332
ISSN:
0169-5002
URN:
uuid:1f3e1f62-17f1-4f1f-92a4-79b07e5fe5de
Source identifiers:
486713
Local pid:
pubs:486713

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