Journal article
A sperm-specific proteome-scale metabolic network model identifies non-glycolytic genes for energy deficiency in asthenozoospermia
- Abstract:
-
About 15% of couples experience difficulty in conceiving a child, of which half of the cases are thought to be male-related. Asthenozoospermia, or low sperm motility, is one of the frequent types of male infertility. Although energy metabolism is suggested to be central to the etiology of asthenozoospermia, very few attempts have been made to identify its underlying metabolic pathways. Here, we reconstructed SpermNet, the first proteome-scale model of the sper...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Publisher copy:
- 10.1080/19396368.2016.1263367
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Authors
Funding
Bibliographic Details
- Publisher:
- Taylor and Francis Publisher's website
- Journal:
- Systems Biology in Reproductive Medicine Journal website
- Volume:
- 63
- Issue:
- 2
- Pages:
- 100-112
- Publication date:
- 2017-01-13
- Acceptance date:
- 2016-10-01
- DOI:
- EISSN:
-
1939-6376
- ISSN:
-
1939-6368
- Pmid:
-
28085499
- Source identifiers:
-
827867
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:827867
- UUID:
-
uuid:1f26ae3c-26e4-4021-8a70-6943920723bc
- Local pid:
- pubs:827867
- Deposit date:
- 2018-03-08
Terms of use
- Copyright holder:
- Taylor & Francis
- Copyright date:
- 2017
- Rights statement:
- © 2017 Taylor & Francis
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