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Journal article

Effect of central cholinergic stimulation on regional cerebral blood flow in Alzheimer disease.

Abstract:
Patients with Alzheimer disease (AD) had reduced regional cerebral blood flow (rCBF) in the posterior parietotemporal region compared with controls, as determined with technetium-99m hexamethyl propyleneamine oxime and single photon emission tomography. Central cholinergic stimulation with physostigmine produced a focal increase in rCBF in the posterior parietotemporal region in the patients with AD but not in controls.
Publication status:
Published

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Journal:
Lancet
Volume:
335
Issue:
8704
Pages:
1484-1487
Publication date:
1990-06-01
DOI:
EISSN:
1474-547X
ISSN:
0140-6736
Source identifiers:
185820

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