Journal article
Specifically horizontally tethered DNA probes on Au surfaces allow labelled and label-free DNA detection using SERS and electrochemically driven melting
- Abstract:
-
Controlled covalent attachment of dsDNA horizontally orientated on a gold surface is achieved through the use of a single surface-linker located approximately half way along the attached DNA probe strand. We show that horizontally oriented dsDNA on a gold surface can undergo melting and re-hybridization to target strand in solution and thus can be used for the detection of specific target DNA sequences using surface-enhanced Raman spectroscopy (SERS). We show that a range of lengths of target...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Authors
Funding
Royal Society
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Bibliographic Details
- Publisher:
- Royal Society of Chemistry Publisher's website
- Journal:
- Chemical Science Journal website
- Volume:
- 7
- Issue:
- 1
- Pages:
- 386-393
- Publication date:
- 2015-10-08
- Acceptance date:
- 2015-10-08
- DOI:
- EISSN:
-
2041-6539
- ISSN:
-
2041-6520
Item Description
- Pubs id:
-
pubs:590222
- UUID:
-
uuid:1ef9778b-6055-4c45-b8fd-572c34afd31d
- Local pid:
- pubs:590222
- Source identifiers:
-
590222
- Deposit date:
- 2016-03-01
Terms of use
- Copyright holder:
- Brown et al
- Copyright date:
- 2015
- Notes:
- © The Royal Society of Chemistry 2016. This article is freely available. This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
- Licence:
- CC Attribution (CC BY)
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