Journal article
Synthesis of fluorescence-labelled disaccharide substrates of glucosidase II.
- Abstract:
-
The fluorescence-labelled disaccharides Glcalpha(1-->3)GlcalphaOR and Glcalpha(1-->3)ManalphaOR, both substrates for the glycoprotein-processing enzyme glucosidase II, were synthesised via the use of a n-pentenyl-derived linker at the anomeric position. This allowed incorporation of a pyrenebutyric acid label, via a sequence of oxidative hydroboration, mesylation, azide displacement, reduction with concomitant global deprotection, and peptide coupling. Selective activation of a fully ar...
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- Publication status:
- Published
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Bibliographic Details
- Journal:
- Carbohydrate research
- Volume:
- 338
- Issue:
- 19
- Pages:
- 1937-1949
- Publication date:
- 2003-09-01
- DOI:
- EISSN:
-
1873-426X
- ISSN:
-
0008-6215
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:100115
- UUID:
-
uuid:1eeb33c9-536a-4cea-ad3c-75fab4e5892c
- Local pid:
- pubs:100115
- Source identifiers:
-
100115
- Deposit date:
- 2012-12-19
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- Copyright date:
- 2003
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