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A pilot study of postoperative animal welfare as a guidance tool in the development of a kidney autotransplantation model with extended warm ischemia

Abstract:

Background:
This pilot study aimed to maintain acceptable animal welfare in the development of a porcine autotransplantation model with severe and incremental renal ischemic injury, a model for usage in future intervention studies. Secondary aims were to develop and test methods to collect blood and urine without the need to restrain or use sedative and avoid transportation to optimize welfare of the pig.


Methods:
Kidneys from 7 f...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1097/TXD.0000000000000941

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Surgical Sciences
Role:
Author
Publisher:
Lippincott, Williams & Wilkins Publisher's website
Journal:
Transplantation Direct Journal website
Volume:
5
Issue:
11
Article number:
e495
Publication date:
2019-10-08
Acceptance date:
2019-08-12
DOI:
EISSN:
2373-8731
Pmid:
31773049
Language:
English
Keywords:
Pubs id:
1076052
Local pid:
pubs:1076052
Deposit date:
2020-04-02

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