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Electrohydrodynamic encapsulation of cisplatin in poly (lactic-co-glycolic acid) nanoparticles for controlled drug delivery.

Abstract:

Targeted delivery of potent, toxic chemotherapy drugs, such as cisplatin, is a significant area of research in cancer treatment. In this study, cisplatin was successfully encapsulated with high efficiency (>70%) in Poly (lactic-co-glycolic acid) polymeric nanoparticles by using electrohydrodynamic atomization (EHDA) where applied voltage and solution flow rate as well as the concentration of cisplatin and polymer were varied to control the size of th...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.nano.2016.05.005

Authors


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Institution:
University of Oxford
Division:
MPLS
Department:
Engineering Science
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Engineering Science
Role:
Author
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Publisher:
Elsevier Publisher's website
Journal:
Nanomedicine Journal website
Volume:
12
Issue:
7
Pages:
1919-1929
Publication date:
2016-05-01
Acceptance date:
2016-05-05
DOI:
EISSN:
1549-9642
ISSN:
1549-9634
Source identifiers:
623336
Language:
English
Keywords:
Pubs id:
pubs:623336
UUID:
uuid:1ec7b2cb-671d-4f95-bc82-38b0c076de1f
Local pid:
pubs:623336
Deposit date:
2016-06-24

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