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Competing oscillators in cardiac pacemaking: historical background.

Abstract:

Interaction between a membrane oscillator generated by voltage-dependent ion channels and an intracellular calcium signal oscillator was present in the earliest models (1984 to 1985) using representations of the sarcoplasmic reticulum. Oscillatory release of calcium is inherent in the calcium-induced calcium release process. Those historical results fully support the synthesis proposed in the articles in this review series. The oscillator mechanisms do not primarily compete with each; they en...

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Publication status:
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Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Role:
Author
Journal:
Circulation research More from this journal
Volume:
106
Issue:
12
Pages:
1791-1797
Publication date:
2010-06-01
DOI:
EISSN:
1524-4571
ISSN:
0009-7330
Language:
English
Keywords:
Pubs id:
pubs:237556
UUID:
uuid:1ebfb422-2a1f-4fa7-8f6a-ddf01f77bbdb
Local pid:
pubs:237556
Source identifiers:
237556
Deposit date:
2013-11-16

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