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HIV in Africa (Communication arising): chemokine-receptor genes and AIDS risk.

Abstract:

Schliekelman et al. have provided a model to quantify the speed at which HIV-resistance haplotypes can become enriched in a susceptible population through a delay in the onset of AIDS, permitting greater lifetime reproduction and the selection of AIDS-delaying haplotypes. But we question their conclusion that there could be a rapid evolution of resistance to AIDS onset in some African populations if the current HIV epidemic persists, as this depends on an untested assumption: that variant for...

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Publisher copy:
10.1038/417140a

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Journal:
Nature More from this journal
Volume:
417
Issue:
6885
Pages:
140
Publication date:
2002-05-01
DOI:
EISSN:
1476-4687
ISSN:
0028-0836

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