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Reappraising the variability of effects of antipsychotic medication in schizophrenia: a meta-analysis

Abstract:

It is common experience for practising psychiatrists that individuals with schizophrenia vary markedly in their symptomatic response to antipsychotic medication. What is not clear, however, is whether this variation reflects variability of medication-specific effects (also called “treatment effect heterogeneity”), as opposed to variability of non-specific effects such as natural symptom fluctuation or placebo response. Previous meta-analyses found no evidence of treatment effect heterogeneity...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1002/wps.20977

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Name:
National Institute for Health Research
Grant:
RP-2017-08-ST2-006
Publisher:
Wiley
Journal:
World Psychiatry More from this journal
Volume:
21
Issue:
2
Pages:
287-294
Publication date:
2022-05-07
Acceptance date:
2022-01-21
DOI:
EISSN:
2051-5545
ISSN:
1723-8617

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