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Differential susceptibility of retroviruses to nucleoside analogues.

Abstract:

Retroviruses may cause diseases in their vertebrate hosts. They are distinguished by their common means of replication involving reverse transcription, a process inhibited by nucleoside reverse transcriptase inhibitors (NRTIs) and other compounds used in antiretroviral chemotherapy. Previous work on NRTIs has been limited to their effect on human immunodeficiency virus (HIV) (for review see Ho and Hitchcock, 1989; Weller, 1999) and little information exists regarding the efficacy and therapeu...

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Publication status:
Published

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Authors


Rosenblum, LL More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Experimental Medicine Division,
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Journal:
Antiviral chemistry and chemotherapy
Volume:
12
Issue:
2
Pages:
91-97
Publication date:
2001-03-05
EISSN:
2040-2066
ISSN:
0956-3202
URN:
uuid:1e8519e7-fe80-4b57-8a98-ce57e3a94d5d
Source identifiers:
27390
Local pid:
pubs:27390

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