Journal article icon

Journal article

Big brains, meat, tuberculosis, and the nicotinamide switches: co-evolutionary relationships with modern repercussions?

Abstract:

Meat-eating was a game changer for human evolution. We suggest that the limiting factors for expanding brains earlier were scarcities of nicotinamide and tryptophan. In humans and some other omnivores, lack of meat causes these deficiencies. Nicotinamide adenine dinucleotide (NADH) is necessary to synthesize adenosine triphosphate (ATP) via either glycolysis or via the mitochondrial respiratory chain. NAD consumption is also necessary for developmental and repair circuits. Inadequate supplies...

Expand abstract

Actions


Access Document


Publisher copy:
10.4137/ijtr.s12838

Authors


Williams, AC More by this author
Dunbar, RI More by this author
Journal:
International journal of tryptophan research : IJTR
Volume:
6
Pages:
73-88
Publication date:
2013
DOI:
EISSN:
1178-6469
URN:
uuid:1e7dffea-485f-4178-b2d9-7a7c0567d56d
Source identifiers:
440080
Local pid:
pubs:440080

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP