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Measuring venous blood volume changes during activation using hyperoxia.

Abstract:

This study describes a novel method for measuring relative changes in venous cerebral blood volume (CBVv) using hyperoxia as a contrast agent. This method exploits the extravascular BOLD effect and its dependency on both task-related activation induced changes in venous blood oxygenation and changes due to breathing an oxygen enriched gas mixture. Changes in CBVv on activation can be estimated by comparing the change in transverse relaxation rate, R2*, due to hyperoxia in both baseline and ac...

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine
Role:
Author
Journal:
NeuroImage
Volume:
59
Issue:
4
Pages:
3266-3274
Publication date:
2012-02-05
DOI:
EISSN:
1095-9572
ISSN:
1053-8119
URN:
uuid:1e78b1aa-ba75-41c4-abcc-692a6c7c36fd
Source identifiers:
255630
Local pid:
pubs:255630

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